December 5 – 6, 2022 | Washington DC, USA

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Metabolic, Hepatology, Nephrology and Cardiovascular Cross Talk
Cardiologist, endocrinologist and hepatologist trialists, industry, regulatory experts, payers, patients representatives and other stakeholders crosstalk summit.
A Multi-stakeholder Multi-specialty NASH Trialists Think Tank

A Multi-stakeholder Multi-specialty NASH Trialists Think Tank

Metabolic, Hepatology, Nephrology and Cardiovascular Cross Talk

Organized by the Translational Medicine Academy

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In collaboration with CardioVascular Clinical Trialists Forum 

and Liver forum

Endorsed by the Stravitz-Sanyal Institute for Liver Disease and Metabolic Health
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Overview Topics Speakers Learning Objectives Agenda
Overview
MOSAIC - the 1st Global NASH Trialist Forum
will bring together cardiology, endocrinology & hepatology clinicial trialists, industry, regulatory experts, payers, patients representatives and other stakeholders to further advance collective intelligence and foster collaboration about NASH diagnosis and management.
NASH: a major unmet need in clinical trial science
it is now clear that non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are a public health problem worldwide.
• It affects around 25-30% of the adult population and causes considerable liver-related and extra-hepatic morbidity and mortality.
• NASH is considered a metabolic and multi organ disease with cardiovascular complications, worsening metabolic dysfunction and other extra-hepatic diseases, such as type 2 diabetes mellitus (T2DM), chronic kidney disease (CKD), or certain extra-hepatic cancers.
MOSAIC - the 1st Global Nash Trialist Forum
will bring together cardiology, endocrinology & hepatology clinicial trialists, industry, regulatory experts, payers, patients representatives and other stakeholders to further advance collective intelligence and foster collaboration about NASH diagnosis and management.
NASH: a major unmet need in clinical trial science
it is now clear that non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) are a public health problem worldwide.
• It affects around 25-30% of the adult population and causes considerable liver-related and extra-hepatic morbidity and mortality.
• NASH is considered a metabolic and multi organ disease with cardiovascular complications, worsening metabolic dysfunction and other extra-hepatic diseases, such as type 2 diabetes mellitus (T2DM), chronic kidney disease (CKD), or certain extra-hepatic cancers.
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Learning Objectives
Why you should attend?
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    Networking opportunities
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    Think Tank focused Workshops
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    Latest trials updates
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    Patient participation
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Chairs
Stephen Harrison
USA
Veronica Miller
USA
Arun-Sanyal-USA
Arun Sanyal
USA
Ellipse chair
Faiez Zannad
France
Thursday 30 June 2022
View PDF programme Session agenda
Topics
  • NASH – Cardiovascular Intersections
  • Epidemiology, disease mechanisms
  • NonInvasive Tests (NITs)
  • Trial design issues and innovations
  • Patient population selection in NASH trials
  • Endpoints
  • Pathways to approval
  • Therapeutics
  • Experiences and case studies
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Friday 1 July 2022
View PDF programme Session agenda
Presentations and Discussion
  • How do SGLT2 inhibitors bring about cardiorenal benefits?
    Subodh Verma, Toronto, ON, Canada
  • Totality of evidence in heart failure
    Deepak L. Bhatt, Boston, MA, USA
  • Trial results coming out soon
    Stefan D. Anker, Berlin, Germany
  • Heart failure guidelines – July 2021 update
    Marco Metra, Brescia, Italy
  • Panel Discussion
Meet The Expert Breakout Sessions
  • Early treatment initiation in the hospital setting
    Mark C. Petrie, Glasgow, UK
    Deepak L. Bhatt, Boston, MA, USA
  • Managing patients with comorbidities (T2D & CKD)
    Paola Fioretto, Padova, Italy
    Katherine R. Tuttle, Spokane, WA, USA
  • Interdisciplinary collaboration and care transitions
    Subodh Verma, Toronto, ON, Canada
    Faiez Zannad, Nancy, France
Industry-Sponsored Satellite Symposia
  • Details coming soon
Programs
  • Session 7: Use of NITS for efficacy and safety assessment- circulating biomarkers
  • Session 8: Use of NITs for efficacy and safety assessment- Imaging
  • Session 9: Therapeutics
  • Session 10: Breakout sessions and report back
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